CD144 (VE-Cadherin), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD144 (VE-Cadherin), Mouse |
| Clone | REA225 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | APC-Vio 770 conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD144 (VE-Cadherin) Antibody, anti-mouse, APC-Vio® 770, REAfinity™. Clone REA225 recognizes mouse CD144, which is also known as cadherin 5 or vascular endothelial cadherin (VE-Cadherin). This calcium-dependent cell-cell adhesion glycoprotein is composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. CD144 is a strictly endothelial specific adhesion molecule located at junctions between endothelial cells and is of vital importance for the maintenance and control of endothelial cell contacts. Mechanisms that regulate VE-cadherin-mediated adhesion are important for the control of vascular permeability and leukocyte extravasation. CD144 also regulates various cellular processes such as cell proliferation and apoptosis and modulates vascular endothelial growth factor receptor functions. | Additional information: Clone REA225 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CDH5, 7B4, VE-Cad, VECD, VEcad, Vec |
| Gene, Accession # | Gene ID: 12562 |
| Catalog # | 130-123-480 |
| Price | $125 |
| Order / More Info | CD144 (VE-Cadherin), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Vestweber, D. et al. (2008) VE-Cadherin: The major endothelial adhesion molecule controlling cellular junctions and blood vessel formation. Arterioscler. Thromb. Vasc. Biol. 28: 223-232. | Lampugnani, M. G. et al. (1992) A novel endothelial-specific membrane protein is a marker of cell-cell contacts. J. Cell Biol. 118: 1511. | Ali, J. et al. (1997) Vascular endothelial cadherin (VE-cadherin): cloning and role in endothelial cell-cell adhesion. MIcrocirculation 4 (2): 267-277. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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