CD152, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD152, Human |
| Clone | REA1003 |
| Host Species | Recombinant Human |
| Reactive Species | human, nonhuman primate |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD152 Antibody, anti-human, APC, REAfinity™. Clone REA1003 recognizes the human CD152, an integral membrane protein of the immunoglobin superfamily which is also called CTLA-4. CD152 is a negative regulator of T cell activation. It is transiently expressed on activated CD28+ T cells and is a ligand for CD80 and CD86. CD4+FoxP3+ regulatory T cells are reported to constitutively express CD152. CD152 may also be detected on B cells when cultured with activated T cells. | Additional information: Clone REA1003 displays negligible binding to Fc receptor. |
| Immunogen | n/a |
| Other Names | CTLA4, ALPS5, CD, CELIAC3, CTLA-4, GRD4, GSE, IDDM12, CTLA-4 |
| Gene, Accession # | Gene ID: 1493 |
| Catalog # | 130-116-931 |
| Price | $140 |
| Order / More Info | CD152, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Kuiper, H. M. et al. (1995) Activated T cells can induce high levels of CTLA-4 expression on B cells. J Immunol 155 (4): 1776-1783. | Castan, J. et al. (1997) Accumulation of CTLA-4 expressing T lymphocytes in the germinal centres of human lymphoid tissues. Immunology 90 (2): 265-271. | Schlotmann, T. et al. (2000) CD alphabeta T lymphocytes express high levels of the T lymphocyte antigen CTLA-4 (CD152) in acute malaria. J. Infect. Dis. 182 (1): 367-370. | Sansom, D. M. and Walker, L. S. (2006) The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology. Immunol. Rev. 212: 131-148. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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