Ly-49G, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Ly-49G, Mouse |
| Clone | REA1022 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Ly-49G Antibody, anti-mouse, FITC, REAfinity™. Clone REA1022 recognizes the type II transmembrane protein Ly-49G, which is a MHC class I receptor also known as Kira-7. It is expressed on NK, NKT, and T cells. It is reported that the binding of Ly-49G with its ligand leads to inhibition of NK cells, T cells cytotoxicity, cytokine production, and proliferation. The antibody reacts with Ly49G receptor of A/J, BALB/c, C3H, CBA,129, FVB, and SJL mice, but not C57BL/6 mice. | Additional information: Clone REA1022 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Klra7, LGL-1, Ly49G.4, Ly49g1, Kira-7, Ly49G2 |
| Gene, Accession # | Gene ID: 16638 |
| Catalog # | 130-117-274 |
| Price | $54 |
| Order / More Info | Ly-49G, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Makrigiannis, A. P. et al. (2004) Independent control of Ly49g alleles: implications for NK cell repertoire selection and tumor cell killing. J Immunol 172: 1414-1425. | Rouhi, A. et al. (2007) Plasticity of Ly49g expression is due to epigenetics. Mol. Immunol. 44 (5): 821-826. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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