CD44H, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD44H, Rat
CloneREA505
Host SpeciesRecombinant Human
Reactive Speciesrat
IsotypeIgG1
Formatfluorescein (FITC) conjugate
Size30 µg in 1 mL
Concentration1:10
ApplicationsFlow cytometry
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DescriptionCD44H Antibody, anti-rat, FITC, REAfinity™. Clone REA505 recognizes the rat CD44H antigen, a transmembrane glycoprotein, also known as homing-associated cell adhesion molecule (H-CAM) or phagocytic glycoprotein-1 (Pgp-1). CD44H belongs to the CD44 group, that encompasses several isoforms expressed in a variety of tissues. It is highly expressed on hematopoietic and non-hematopoietic cells. All isoforms are encoded by the same gene on chromosome 11 and are formed by alternative splicing of their mRNA. CD44 isoforms belong to the family of cell adhesion molecules and to the sub-family of the hyaladherins in consideration of their affinity for hyaluronate and their structural homology with the cartilage link protein. The standard form of CD44, CD44H, exhibits a high affinity for hyaluronate, plays a role in the uptake and degradation of this glycosaminoglycan, and participates in cell locomotion in its presence. | Additional information: Clone REA505 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesCD44s, CD44A, METAA, RHAMM, CD44, Pgp-1, H-CAM, CD44st, CD44std
Gene, Accession #Gene ID: 25406
Catalog #130-107-801
Price$50
Order / More InfoCD44H, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesZheng, Z. et al. (1995) Monoclonal antibodies to CD44 and their influence on hyaluronan recognition. J. Cell Biol. 130 (2): 485-495. | Thomas, L. (1993) CD44, the hyaluronic acid cell receptor. Its role in neoplastic invasion and metastatic dissemination. Bull Cancer 80 (10): 833-844.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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