TROP2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TROP2, Human |
| Clone | REA916 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Vio Bright V423 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TROP2 Antibody, anti-human, Vio® Bright V423, REAfinity™. Clone REA916 recognizes the human TROP2 antigen, a type I membrane glycoprotein also known as tumor-associated calcium signal transducer 2 (TACSTD2). TROP2 acts as a signal transducer and may be involved in regulating the growth of carcinoma cells. It is strongly expressed by a variety of human carcinomas, but also on trophoblasts and epithelial cells. | Additional information: Clone REA916 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | TACSTD2, GA733-1, M1S1, TROP2, EGP-1 |
| Gene, Accession # | Gene ID: 4070 |
| Catalog # | 130-128-658 |
| Price | $208 |
| Order / More Info | TROP2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Fornaro, M. et al. (1995) Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas. Int. J. Cancer 62 (5): 610-618. | Ripani, E. et al. (1998) Human Trop-2 is a tumor-associated calcium signal transducer. Int. J. Cancer 76 (5): 671-676. | Cubas, R. et al. (2010) Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway. Mol. Cancer 9: . |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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