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Antigenic Specificity | CD44, Mouse |
Clone | IM7.8.1 |
Host Species | Rat |
Reactive Species | mouse, nonhuman primate, other |
Isotype | IgG2bκ |
Format | phycoerythrin (PE) conjugate |
Size | 9 µg in 300 µL |
Concentration | 1:10 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD44 Antibody, anti-mouse, PE. Mouse CD44 is also known as Pgp-1, HCELL, HUTCH-I, HCAM, HERMES, and Ly-24. Clone IM7 reacts with murine CD44, an 80-95 kDa membrane glycoprotein. It is expressed by a variety of hematopoetic and non-hematopoetic cells. Different isoforms are generated by alternative splicing. Clone IM7 reacts with all isoforms and both allelic forms of CD44. CD44 functions as a receptor for hyaluronic acid (HA) and mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 expression is upregulated on naive T cells upon activation and high CD44 expression is maintained on memory T cells. Therefore, CD44 is often used to discriminate CD44highantigen-experienced T cells from CD44low (CD62L+) naive T cells. |
Immunogen | n/a |
Other Names | HERMES, Ly-24, Pgp-1, CD44s, EMCR III, H-CAM |
Gene, Accession # | Gene ID: 12505 |
Catalog # | 130-102-982 |
Price | $54 |
Order / More Info | CD44, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Ponta, H. et al. (2003) CD44: From adhesion molecules to signalling regulators. Nat. Rev. Mol. Cell Biol. 4 (1): 33-45. |