Ly-49A, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-Ly-49A, Mouse antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Ly-49A, Mouse |
| Clone | REAL436 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Ly-49A Antibody, anti-mouse, APC, REAlease®. Clone REAL436 is an antibody fragment derived from the full Ly-49A antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL436 recognizes th mouse Ly49A antigen, an inhibitory cell surface receptor belonging to the Ly49 receptor family. Ly49A is a 44 kDa type-II transmembrane, disulfide-linked homodimer with C-type lectin extracellular domains. Expression of Ly49A is found on subset of NK and NK-T cells. Ly49 family members are both activating and inhibitory receptors and are mainly receptors for MHC class I molecules. Ly49A interacts strongly with MHC class Ia molecules such as H-2Dd, H-2Dk and weakly with H-2Db. An inhibitory signal is delivered by Ly49A engagement via the phosphorylation of immunoreceptor tyrosine based inhibition motif (ITIM) and recruitment of phosphatases SHP-1 and SHP-2. Recognition of cognate ligand bearing cells leads to inhibition of cytotoxic killing of cells by NK cells. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes. |
| Immunogen | n/a |
| Other Names | Klra1, CH29-493D4.3, Klra22, Ly49v |
| Gene, Accession # | n/a |
| Catalog # | 130-121-363 |
| Price | $109 |
| Order / More Info | Ly-49A, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | n/a |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies