CD11c, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD11c, Mouse |
| Clone | REAL114 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD11c Antibody, anti-mouse, PE, REAdye_lease™. Clone REAL114 is an antibody fragment derived from the full CD11c antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL114 recognizes the mouse CD11c antigen, also known as Integrin αX or Itgax. CD11c is a receptor for fibrinogen. It mediates cell-cell interaction during inflammatory responses and is involved in monocyte adhesion and chemotaxis. CD11c is present in dendritic cells in lymphoid organs and blood, in Langerhans cells in the epidermis, in dendritic cell progenitors in the bone marrow, and in in vitro generated bone marrow-derived dendritic cells. It is also expressed in spleen and lymph node, and weakly expressed on NK cells, B cells, and T cell subsets. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
| Immunogen | n/a |
| Other Names | p150, integrin αX, ITGAX, CR4, Integrin alpha-X, CD11 antigen-like family member C |
| Gene, Accession # | n/a |
| Catalog # | 130-129-897 |
| Price | $410 |
| Order / More Info | CD11c, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Springer, T. A. (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76 (2): 301-314. | Lopez-Rodriguez, C. et al. (1996) AP-1 regulates the basal and developmentally induced transcription of the CD11c leukocyte integrin gene. J Immunol 156 (10): 3780-3787. | Hou, L. et al. (2020) CD11c regulates hematopoietic stem and progenitor cells under stress. Blood Adv 4 (24): 6086-6097. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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