CD22, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD22, Mouse |
| Clone | REA1187 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | PE-Vio 770 conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD22 Antibody, anti-mouse, PE-Vio® 770, REAfinity™. Clone REA1187 recognizes the 150 kDa B cell-restricted glycoprotein CD22 on mice strains having the Lyb-8.2 alloantigen, e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, and SWR. Lyb-8.2 is expressed at mature levels on all B cell subsets. In bone marrow, CD22 is not detectable on pro-B cells, pre-B cells, and emerging IgM+ B cells. CD22 plays a strong role in cell interactions and B cell activation. | Additional information: Clone REA1187 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | BL-CAM, SIGLEC-2, Lyb-8 |
| Gene, Accession # | Gene ID: 12483 |
| Catalog # | 130-122-048 |
| Price | $165 |
| Order / More Info | CD22, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Symington, F. W. et al. (1982) Lyb-8.2: A new B cell antigen defined and characterized with a monoclonal antibody. Immunogenetics 16 (5): 381-391. | Law, C. L. et al. (1994) Regulation of lymphocyte activation by the cell-surface molecule CD22. Immunol. Today 15 (9): 442-449. | Erickson, L. D. et al. (1996) Differential expression of CD22 (Lyb8) on murine B cells. Immunogenetics 8 (7): 1121-1129. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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