CX3CR1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCX3CR1, Human
Clone2A9-1
Host SpeciesRat
Reactive Specieshuman
IsotypeIgG2bκ
Formatphycoerythrin (PE) conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsFlow cytometry
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DescriptionCX3CR1 Antibody, anti-human, PE. CX3CR1 is a transmembrane chemokine receptor with a molecular mass of 40 kDa. It binds the chemokine CX3CL1, also known as fractalkine or neurotactin. Binding of CX3CR1 to the membrane?bound form of fractalkine promotes cell-cell adhesion, wheras the soluble form induces cell migration of CX3CR1-bearing cells such as monocytes, NK cells, T cells, dendritic cells (DCs), and macrophages including microglia. CX3CR1 plays also an important role in the formation of transepithelial dendrites by intestinal DCs. Failure in the fractalkine/CX3CR1 interaction may contribute to the development of several inflammatory diseases including atherosclerosis, psoriasis, rheumatoid arthritis, and experimental autoimmune myositis.
Immunogenn/a
Other NamesCCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28
Gene, Accession #Gene ID: 1524
Catalog #130-096-432
Price$310
Order / More InfoCX3CR1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesNiess, J. H. et al. (2005) CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 307: 254-258. | Imai, T. et al. (1997) Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell 91: 521-530.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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