CD25, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD25, Human
CloneREA570
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
FormatAPC-Vio 770 conjugate
Size30 tests in 60 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionCD25 Antibody, anti-human, APC-Vio® 770, REAfinity™. Clone REA570 recognizes the human CD25 glycoprotein, also known as the low-affinity interleukin-2 receptor alpha chain (IL-2Rα). It associates with IL-2 receptor β (CD122) and γ chains (CD132) to form a high affinity IL-2R complex. CD25 is expressed on activated T and B cells, on macrophages, and on a subset of non-activated CD4+ regulatory T cells. Clone REA570 recognizes epitope region A. | Additional information: Clone REA570 displays negligible binding to Fc receptors
Immunogenn/a
Other NamesIL2RA, IDDM10, IL2R, TCGFR, p55, Tac
Gene, Accession #Gene ID: 3559
Catalog #130-123-585
Price$148
Order / More InfoCD25, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesLee, S. H. et al. (2012) Cutting edge: a novel mechanism bridging innate and adaptive immunity: IL-12 induction of CD25 to form high-affinity IL-2 receptors on NK cells. J Immunol 189 (6): 2712-2716. | Piccirillo, C. A. et al. (2006) Development and function of naturally occurring CD4+ CD25+ regulatory T cells. J. Leukoc. Biol. 3: 458-470. | Goudy, K. et al. (2013) Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity. Clin. Immunol. 146 (3): 248-261.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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