CD357 (GITR), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD357 (GITR), Mouse |
| Clone | DTA-1 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2bκ |
| Format | Vio Bright B515 conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Functional assay |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD357 (GITR) Antibody, anti-mouse, Vio® Bright B515. Clone DTA-1 specifically recognizes mouse CD357, also known as glucocorticoid-induced TNF-receptor (GITR) or TNFRSF18, a member of the TNF receptor superfamily. It is expressed at low levels on resting T lymphocytes and at high levels on CD4+CD25+ regulatory T cells (Tregs). Activation of T cells upregulates GITR expression. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production, as well as MAPKs and NF-κB activation. GITR plays an important role in the function of CD4+CD25+ Tregs. |
| Immunogen | n/a |
| Other Names | TNFRSF18, AITR |
| Gene, Accession # | Gene ID: 21936 |
| Catalog # | 130-129-328 |
| Price | $199 |
| Order / More Info | CD357 (GITR), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | n/a |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG