CD158e/k (KIR3DL1/DL2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD158e/k (KIR3DL1/DL2), Human |
| Clone | REA970 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | PE-Vio 770 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD158e/k (KIR3DL1/DL2) Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA970 recognizes the human CD158e (KIR3DL1) and CD158k (KIR3DL2) antigens, members of the killer immunoglobulin-like receptor (KIR) family which recognizes subsets of HLA alleles. The family of KIR contributes to the regulation of NK cell-mediated cytotoxicity. Expression is found mainly on CD56dimCD16+ natural killer (NK) cells but also on a subset of CD8+ T cells. They are monomeric receptors possessing high allelic polymorphism with either two or three Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be subdivided in inhibitory KIRs and activating KIRs. | Additional information: Clone REA970 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | KIR3DL1, KIR3DL2 |
| Gene, Accession # | Gene ID: 3811 |
| Catalog # | 130-116-283 |
| Price | $164 |
| Order / More Info | CD158e/k (KIR3DL1/DL2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Yawata, M. et al. (2002) Variation within the human killer cell immunoglobulin-like receptor (KIR) gene family. Crit. Rev. Immunol. 22 (5-6): 463-482. | Uhrberg, M. (2005) The KIR gene family: life in the fast lane of evolution. Eur. J. Immunol. 35 (1): 10-15. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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