Edit |   |
Antigenic Specificity | CD49b, Human |
Clone | REA188 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 100 tests in 1 mL |
Concentration | 1:11 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD49b Antibody, anti-human, FITC, REAfinity™. Clone REA188 recognizes CD49b, also known as integrin α2 chain. CD49b is single-pass, 150 KDa, type I membrane protein. Together with integrin β1 (CD29), CD49b forms the VLA-2 receptor, which binds ligands such as collagen, fibrinogen, and laminin and thus mediate the attachment of several cell types to extracellular matrix. Expression of CD49b is found on lymphocytes, activated T cells, monocytes, epithelial cells, and platelets. | Additional information: Clone REA188 displays negligible binding to Fc receptors. | |
Immunogen | n/a |
Other Names | Itga2, BR, α2 integrin, gpIa, HPA-5, VLA-2, VLAA2, CD49b, VLA-2α |
Gene, Accession # | Gene ID: 3673 |
Catalog # | 130-100-337 |
Price | $264 |
Order / More Info | CD49b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Elices, M. J. and Hemler, M. E. (1989) The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others. Proc. Natl. Acad. Sci. U.S.A. 86: 9906-9910. |