CD11c, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD11c, Human
CloneMJ4-27G12
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b
FormatVioBlue conjugate
Size100 tests in 200 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionCD11c Antibody, anti-human, VioBlue®. This CD11 antibody reacts with human CD11c, a 145-150 kDa type I transmembrane glycoprotein, which is also known as integrin αX or CR4. It is expressed on monocytes, macrophages, NK cells, granulocytes, myeloid dendritic cells (MDCs), and subsets of T and B cells. | On myeloid dendritic cells, CD11c is highly expressed on type 1 myeloid dendritic cells (CD1c (BDCA-1)+ CD123low MDC1s) and low on type 2 myeloid dendritic cells (CD1c (BDCA-1)- CD123- MDC2s). | CD11c, also known as integrin integrin αX or CR4, has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.
Immunogenn/a
Other NamesITGAX, CR4, SLEB6, 95, integrin αX, p150
Gene, Accession #Gene ID: 3687
Catalog #130-113-583
Price$335
Order / More InfoCD11c, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesDzionek, A. et al. (2000) BDCA-2, BDCA-3, BDCA-4: Three markers for distinct subsets of dendritic cells in human peripheral blood. J Immunol 165: 6037-6046. | Bendiss-Vermare, N. et al. (2001) Human thymus contains IFN-alpha-producing CD11c-, myeloid CD11c+, and mature interdigitating dendritic cells. J. Clin. Invest. 107: 835-844. | Barclay, A. N. et al. (1997) In: The Leukocyte Antigen Facts Book, Academic Press, San Diego, CA. (2nd edition): 161-162.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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