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Antigenic Specificity | IFN-γR β chain, Mouse |
Clone | REA381 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 9 µg in 300 µL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IFN-γR β chain Antibody, anti-mouse, APC, REAfinity™. Clone REA381 recognizes the mouse IFN-γ receptor β chain antigen, a type 1 transmembrane protein also known as IFN-γ accessory factor 1 (AF-1). The IFN-γR β chain pairs with CD119 to form the IFN-γ receptor. It is expressed at low levels on T and B cells, NK cells, monocytes, macrophages, and fibroblasts. IFN-γ induces several biologic effects in target cells, including antiviral and antiproliferative responses, expression of major histocompatibility complex and of Fc receptor genes, and immunoglobulin class switching. | Additional information: Clone REA381 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | IFNGR2, IFGR2, Ifgt, AF-1, IFNGRB, IFNGT1, IFNγ R2, IFNγ Rβ |
Gene, Accession # | Gene ID: 15980 |
Catalog # | 130-105-719 |
Price | $67 |
Order / More Info | IFN-γR β chain, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Marsters, S. A. et al. (1995) Interferon gamma signals via a high-affinity multisubunit receptor complex that contains two types of polypeptide chain. Proc. Natl. Acad. Sci. U.S.A. 92 (12): 5401-5405. | Hemmi, S. et al. (1994) A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in human cells. Cell 76 (5): 803-810. | Ebensperger, C. et al. (1996) Genomic organization and promoter analysis of the gene ifngr2 encoding the second chain of the mouse interferon-gamma receptor. Scand. J. Immunol. 44 (6): 599-606. |