CD122 (IL-2Rβ), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD122 (IL-2Rβ), Mouse |
| Clone | TM-β1 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2bκ |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 1 mL |
| Concentration | 1:10 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD122 (IL-2Rβ) Antibody, anti-mouse, PE. The monoclonal antibody TM-β1 recognizes the murine CD122 70-75 kDa cell surface glycoprotein, also known as interleukin-2 receptor beta chain (IL-2Rβ). CD122 is constitutively expressed on mouse NK cells and at a lower level on subsets of T cells, B cells, monocytes, and macrophages. CD122 can associate with the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25), resulting in intermediate or high affinity IL-2 receptor complexes. CD122 expression levels can be upregulated by activation. The TM-β1 antibody interferes with binding of IL-2 to the receptor and can be used to deplete CD122+ cells. |
| Immunogen | n/a |
| Other Names | IL2RB, IL-15Rbeta, Il-2/15Rbeta, Il-2Rbeta, p70, IL-2Rβ |
| Gene, Accession # | Gene ID: 16185 |
| Catalog # | 130-102-569 |
| Price | $67 |
| Order / More Info | CD122 (IL-2Rβ), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Tanaka, T. et al. (1991) A novel monoclonal antibody against murine IL-2 receptor beta-chain. Characterization of receptor expression in normal lymphoid cells and EL- 4 cells. J Immunol 147: 2222-2228. | Tang, Y. et al. (2011) Emergence of NK cell progenitors and functionally competent NK cell lineage subsets in the early mouse embryo. Blood 120: 63-75. | Taniguchi, T. et al. (1993) The IL-2/IL-2 receptor system: a current overview. Cell 73 (1): 5-8. | Malek, T. R. et al. (1995) Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits. J. Interferon Cytokine Res. 15 (5): 447-454. | Nishikawa, Y. et al. (2010) Roles of CD122+ cells in resistance against Neospora caninum infection in a murine model. J. Vet. Med. Sci. 72 (10): 1275-1282. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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