CD137, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-CD137, Human antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CD137, Human |
| Clone | 4B4-1 |
| Host Species | Mouse |
| Reactive Species | human, nonhuman primate |
| Isotype | IgG1κ |
| Format | Vio Bright FITC conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD137 Antibody, anti-human, Vio® Bright FITC. This antibody recognizes the CD137 (4-1BB) antigen, a 30 kDa glycoprotein of the tumor necrosis factor (TNF) receptor superfamily. CD137 is mainly expressed on activated CD4+ and CD8+ T cells, activated B cells, and natural killer cells, but can also be found on resting monocytes and dendritic cells. | As a costimulatory molecule it is involved in the activation and survival of CD4+ or CD8+ T cells, and NK cells. CD137 has been described to be a suitable marker for antigen-specific activation of human CD8+ T cells, as it is not expressed on resting CD8+ T cells and its expression is reliably induced after 24 hours of stimulation. |
| Immunogen | n/a |
| Other Names | TNFRSF9, 4-1BB, CDw137, ILA, 41BB |
| Gene, Accession # | Gene ID: 3604 |
| Catalog # | 130-119-971 |
| Price | $131 |
| Order / More Info | CD137, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Wolfl, M. et al. (2007) Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities. Blood 110: 201-210. | Wehler, T. C. et al. (2007) Targeting the activation-induced antigen CD137 can selectively deplete alloreactive T cells from antileukemic and antitumor donor T-cell lines. Blood 109: 365-373. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies