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Antigenic Specificity | CD183 (CXCR3), Mouse |
Clone | REA724 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | Vio Bright FITC conjugate |
Size | 30 µg in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD183 (CXCR3) Antibody, anti-mouse, Vio® Bright FITC, REAfinity™. Clone REA724 recognizes the mouse CD183 antigen, also known as CXCR3, a 40 kDa seven-transmembrane protein belonging to the the G protein-coupled receptor family that mediates the proliferation, survival, and angiogenic activity of mesangial cells through a heterotrimeric G protein signaling pathway. CD183 binds the ligands CXCL9, CXCL10, and CXCL11 and mediates Ca 2)+ mobilization and chemotaxis. It is expressed on activated T cells, circulating blood T cells, B cells, and NK cells. | Additional information: Clone REA724 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | C-X-C chemokine receptor type 3, CXC-R3, CXCR-3, Interferon-inducible protein 10 receptor, IP-10 receptor |
Gene, Accession # | Gene ID: 12766 |
Catalog # | 130-111-092 |
Price | $98 |
Order / More Info | CD183 (CXCR3), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Tamaru, M. et al. (1998) Cloning of the murine interferon-inducible protein 10 (IP-10) receptor and its specific expression in lymphoid organs. Biochem. Biophys. Res. Commun. 251 (1): 41-48. | Soto, H. et al. (1998) The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3. Proc. Natl. Acad. Sci. U.S.A. 95 (14): 8205-8210. | Huttlin, E. L. et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143 (7): 1174-1189. |