ADAM15, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | ADAM15, Human |
| Clone | REA650 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:10 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ADAM15 Antibody, anti-human, APC, REAfinity™. Clone REA650 recognizes the human ADAM15 antigen, a transmembrane protein, which contains disintegrin and metalloprotease domains. ADAM15 belongs to the membrane linked metalloproteinase family (ADAM), which has gelatinolytic and collagenolytic activities. It has several functions, for example, it is involved in wound healing process and in glomerular cell migration. Furthermore ADAM15 suppresses beta-1 integrins-mediated cell adhesion and migration of smooth muscle cells. | Expression of ADAM-15 is found in airway smooth muscle, glomerular mesangial cells, colon, small testine, and chondrocytes. It is highly expressed in atherosclerotic lesions. | Additional information: Clone REA650 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | ADAM 15, MDC-15, MDC15, Metargidin |
| Gene, Accession # | Gene ID: 8751 |
| Catalog # | 130-109-865 |
| Price | $325 |
| Order / More Info | ADAM15, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | McKie, N. et al. (1997) Expression of members of a novel membrane linked metalloproteinase family (ADAM) in human articular chondrocytes. Biochem. Biophys. Res. Commun. 230 (2): 335-339. | Kratzschmar, J. et al. (1996) Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence. J. Biol. Chem. 271 (9): 4593-4596. | Zhong, J. L. et al. (2008) Distinct functions of natural ADAM-15 cytoplasmic domain variants in human mammary carcinoma. Mol. Cancer Res. 6 (3): 383-394. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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