CD140b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD140b, Human
CloneREA363
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size30 tests in 60 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionCD140b Antibody, anti-human, PE, REAfinity™. Clone REA363 recognizes the human CD140b antigen, a single-pass type I membrane protein, also known as platelet-derived growth factor receptor beta (PDGFR-β). CD140b is broadly expressed in embryonic tissue and in cells of mesodermal origin in adult tissue as fibroblasts, smooth muscle cells, glial cells, and chondrocytes. It is a tyrosine-protein kinase that acts as a cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis, and migration. | Additional information: Clone REA363 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesPDGFRB, IBGC4, IMF1, JTK12, Pdgfr, PDGFR-1
Gene, Accession #Gene ID: 5159
Catalog #130-123-995
Price$114
Order / More InfoCD140b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesGronwald, R. G. et al. (1988) Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class. Proc. Natl. Acad. Sci. U.S.A. 85 (10): 3435-3439. | Jin, S. et al. (2008) Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells. Circ. Res. 102 (12): 1483-1491. | Ball, S. G. et al. (2012) Inhibition of platelet-derived growth factor receptor signaling regulates Oct4 and Nanog expression, cell shape, and mesenchymal stem cell potency. Stem Cells 30 (3): 548-560. | Chi, S. et al. (2016) A CRISPR-based toolbox for studying T cell signal transduction. Biomed Res Int 2016: .
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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