Melanoma (MCSP), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Melanoma (MCSP), Human |
| Clone | REA1041 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | PerCP-Vio 700 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Melanoma (MCSP) Antibody, anti-human, PerCP-Vio® 700, REAfinity™. Clone REA1041 recognizes the melanoma-associated chondroitin sulfate proteoglycan (MCSP) antigen, also known as high molecular weight melanoma-associated antigen. | It has been reported, that Melanoma has a high amino acid sequence homology with AN2 and NG2. MCSP is expressed on the majority (>90%) of human melanoma tissues and melanoma cell lines but not on carcinoma cells, fibroblastoid cells, and cells of hematopoietic origin. | Additional information: Clone REA1041 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CSPG4, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2 |
| Gene, Accession # | Gene ID: 1464 |
| Catalog # | 130-117-623 |
| Price | $158 |
| Order / More Info | Melanoma (MCSP), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Morgan, A. C. et al. (1981) Production and characterization of monoclonal antibody to a melanoma specific glycoprotein. Hybridoma 1: 27-36. | Bumol, T. F. and Reisfeld, R. A. (1982) Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells. Proc. Natl. Acad. Sci. U.S.A. 79 (4): 1245-1249. | Bumol, T. F. et al. (1984) Biosynthetic studies of proteoglycans in human melanoma cells with a monoclonal antibody to a core glycoprotein of chondroitin sulfate proteoglycans. J. Biol. Chem. 259 (20): 12733-12741. | Pluschke, G. et al. (1996) Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan. Proc. Natl. Acad. Sci. U.S.A. 93 (18): 9710-9715. | Benez, A. et al. (1999) Detection of circulating melanoma cells by immunomagnetic cell sorting. J. Clin. Lab. Anal. 13: 229-233. | Siewert, C. et al. (2001) Rapid enrichment and detection of melanoma cells from peripheral blood mononuclear cells by a new assay combining immunomagnetic cell sorting and immunocytochemical staining. Recent Results Cancer Res. 158: 51-60. | Paul, A. K. et al. (2009) Expression of HMP/AN2, a melanoma associated antigen, in murine cerebral gliomas: potential for radioimmunotargeting. J Neurooncol. 94 (1): 21-30. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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