SUSD2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | SUSD2, Human |
| Clone | REA795 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | PE-Vio 615 conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SUSD2 Antibody, anti-human, PE-Vio® 615, REAfinity™. Clone REA795 recognizes the human sushi domain-containing protein 2 (SUSD2) antigen, a single-pass type I membrane protein which is expressed by bone marrow mesenchymal stem cells (MSCs), vessel-surrounding smooth muscle cells, and a few neoplastic cell lines. MSCs are multipotent stromal cells in various adult tissues that can replicate as undifferentiated cells and that have the potential to differentiate to lineages of mesenchymal tissues, including bone, cartilage, fat, tendon, muscle, and marrow stroma. They represent a promising candidate cell population in regenerative medicine and their application in numerous cases demonstrate their therapeutic potential in the regeneration of all skeletal tissues, as well as of soft tissue organs. One particular advantage of MSCs is that they can be used when cells from the target tissue for regeneration are not available. SUSD2 expressing cells reside predominantly in a perivascular location in both basal and functional layers of endometrium. They are able to differentiate into adipocytes, osteocytes, chondrocytes, myocytes, and endothelial cells. SUSD2 is a single marker capable of purifying MSC and reconstituting endometrial stromal tissues in vivo. | Additional information: Clone REA795 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | BK65A6.2, MSC |
| Gene, Accession # | Gene ID: 56241 |
| Catalog # | 130-131-124 |
| Price | $398 |
| Order / More Info | SUSD2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Masuda, H. et al. (2012) A novel marker of human endometrial mesenchymal stem-like cells. Cell Transplant 21 (10): 2201-2214. | Benz, K. et al. (2013) Maintenance of "stem cell" features of cartilage cell sub-populations during in vitro propagation. J. Transl. Med. 11: 27. | Ulrich, D. et al. (2014) Mesenchymal stem/stromal cells in post-menopausal endometrium. Hum. Reprod. 29 (9): 1895-1905. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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