Edit |   |
---|---|
Antigenic Specificity | CD137, Mouse |
Clone | 17B5-1H1 |
Host Species | Hamster |
Reactive Species | mouse |
Isotype | IgG2 |
Format | phycoerythrin (PE) conjugate |
Size | 30 µg in 1 mL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD137 Antibody, anti-mouse, PE. Clone 17B5-1H1 reacts with mouse CD137, also known as 4-1BB or TNFRSF9, a member of the TNFR superfamily. It is expressed on the cell surface of T cells upon activation. The interaction of CD137 with its ligand, 4-1BBL, on antigen presenting cells (APCs) delivers a bidirectional costimulatory signal. CD137 engagement is shown to be required for CD8+ T cell survival and memory formation. The monoclonal antibody 17B5 is reported to have strong antagonistic effect in in vitro functional assays. |
Immunogen | n/a |
Other Names | TNFRSF9, 4-1BB, CDw137, ILA, Ly63, 41BB |
Gene, Accession # | Gene ID: 21942 |
Catalog # | 130-102-568 |
Price | $66 |
Order / More Info | CD137, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | n/a |