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Antigenic Specificity | CD105, Human |
Clone | 43A4E1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1κ |
Format | VioBlue conjugate |
Size | 30 tests in 300 µL |
Concentration | 1:11 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD105 Antibody, anti-human, VioBlue®. The CD105 antigen, also known as endoglin, serves as a receptor for the growth and differentiation factors TGF-β1 and TGF-β3. An epitope of CD105 is recognized by the SH-2 antibody, which was raised against human mesenchymal stromal cells (MSCs) that show mesodermal differentiation capacity. Therefore, it can be used for studies on mesengenesis. CD105 is also expressed on mature endothelial cells and on some leukemic cells of B lymphoid and myeloid origin. |
Immunogen | n/a |
Other Names | ENG, END, HHT1, ORW1 |
Gene, Accession # | Gene ID: 2022 |
Catalog # | 130-099-667 |
Price | $148 |
Order / More Info | CD105, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Barry, F. P. et al. (1999) The monoclonal antibody SH-2, raised against human mesenchymal stem cells, recognizes an epitope on endoglin (CD105). Biochem. Biophys. Res. Commun. 265: 134-139. | Majumdar, M. K. et al. (2000) Isolation, characterization, and chondrogenic potential of human bone marrow-derived multipotential stromal cells. J. Cell. Physiol. 185: 98-106. |