TRA-1-85 (CD147), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TRA-1-85 (CD147), Human |
| Clone | REA476 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TRA-1-85 (CD147) Antibody, anti-human, APC, REAfinity™. Clone REA476 recognizes the human TRA-1-85 antigen, a single-pass type I membrane protein, which is also known as CD147, basigin, or extracellular matrix metalloproteinase inducer (EMMPRIN). TRA-1-85 is expressed by many cell types, including epithelial cells, endothelial cells, leukocytes, and tumor cells. It is present in vascular endothelium in non-neoplastic regions of the brain, and in tumor cells but not in proliferating blood vessels in malignant gliomas. TRA-1-85 has been implicated in a variety of physiological and pathological activities. It is best known for its ability to function as extracellular matrix metalloproteinase inducer, but has also been shown to regulate lymphocyte responsiveness, monocarboxylate transporter expression, and spermatogenesis. TRA-1-85 is often used to discern human cells from non-human cells in multiple applications including animal transplantation studies. | Additional information: Clone REA476 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | EMMPRIN, Basigin (BSG), Neurothelin, 5F7, BSG, TCSF, OKa, CD147 |
| Gene, Accession # | Gene ID: 682 |
| Catalog # | 130-128-900 |
| Price | $149 |
| Order / More Info | TRA-1-85 (CD147), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Biswas, C. et al. (1995) The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res. 55 (2): 434-439. | Williams, B. P. et al. (1988) Biochemical and genetic analysis of the OKa blood group antigen. Immunogenetics 27 (5): 322-329. | Yurchenko, V. et al. (2006) Dealing with the family: CD147 interactions with cyclophilins. Immunology 117 (3): 301-309. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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