CD263 (TRAIL-R3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD263 (TRAIL-R3), Human
CloneDJR3
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1κ
Formatallophycocyanin (APC) conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsFlow cytometry
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DescriptionCD263 (TRAIL-R3) Antibody, anti-human, APC. Clone DJR3 recognizes the human CD263 antigen, a glycophospholipid-anchored cell membrane protein which is also known as TNF-related apoptosis-inducing ligand receptor 3 (TRAIL-R3) or tumor necrosis factor receptor superfamily member 10C (TNFRSF10C). CD263 is the receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain shared by several members of the TNF receptor superfamily and hence is not capable of inducing apoptosis. CD263 is highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung, and heart. It is higher expressed in normal tissues than in tumor cell lines.
Immunogenn/a
Other NamesTNFRSF10C, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID
Gene, Accession #Gene ID: 8794
Catalog #130-104-742
Price$325
Order / More InfoCD263 (TRAIL-R3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesMongkolsapaya, J. et al. (1998) Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): a new receptor protecting lymphocytes from the death ligand TRAIL. J Immunol 160 (1): 3-6. | Degli-Esposti, M. A. et al. (1997) Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family. J. Exp. Med. 186 (7): 1165-1170. | Ursini-Siegel, J. et al. (2007) Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development. Mol. Cell. Biol. 27 (18): 6361-6371.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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