CD301a (MGL1), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD301a (MGL1), Mouse |
| Clone | REA581 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | PE-Vio 770 conjugate |
| Size | 30 µg in 1 mL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD301a (MGL1) Antibody, anti-mouse, PE-Vio® 770, REAfinity™. Clone REA581 recognizes the mouse CD301a antigen, a type II transmembrane glycoprotein also known as macrophage galactose-type C-type lectin-1 (MGL1). CD301 has two genes, CD301a and CD301b, which are highly homologous. In contrast to CD301b, that recognizes N-acetylgalactosamine and galactose, including the O-linked Tn antigen, TF antigen, and core 2, CD301a is highly specific for Lewis X and Lewis A structures. It has been suggested that MGL1 is involved in the clearance of apoptotic cells. CD301a is expressed in alternatively activated macrophages. | Additional information: Clone REA581 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Clec10a, MMGL, M-ASGP-BP-1 |
| Gene, Accession # | Gene ID: 17312 |
| Catalog # | 130-109-218 |
| Price | $167 |
| Order / More Info | CD301a (MGL1), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Raes, G. et al. (2005) Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation. J. Leukoc. Biol. 77 (3): 321-327. | Singh, S. K. et al. (2009) Characterization of murine MGL1 and MGL2 C-type lectins: distinct glycan specificities and tumor binding properties. Mol. Immunol. 46 (6): 1240-1249. | Yuita, H. et al. (2005) Retardation of removal of radiation-induced apoptotic cells in developing neural tubes in macrophage galactose-type C-type lectin-1-deficient mouse embryos. Glycobiology 15 (12): 1368-1375. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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