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Antigenic Specificity | IL-21, Human |
Clone | REA1039 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | Vio R667 conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Intracellular flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-21 Antibody, anti-human, Vio® R667, REAfinity™. Clone REA1039 recognizes the human interleukin 21 (IL-21), which is secreted by a certain subset of CD4+ T cells, called T follicular helper (Tfh) cells, also characterized by the expression of CXCR5 and ICOS and the lineage-specific transcription factor BCL6. But IL-21 production can also be found in other T helper cell lineages and natural killer T (NKT) cells. IL-21 acts in a autocrine manner on Tfh cells and is critical for antibody production by B cells, it enhances natural killer (NK) cell functions, and promotes proliferation of CD8+ T cell. | Additional information: Clone REA1039 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | CVID11, Za11 |
Gene, Accession # | Gene ID: 59067 |
Catalog # | 130-117-423 |
Price | $385 |
Order / More Info | IL-21, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | n/a |