IL-21, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityIL-21, Human
CloneREA1039
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
FormatVio R667 conjugate
Size100 tests in 200 µL
Concentration1:50
ApplicationsIntracellular flow cytometry
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DescriptionIL-21 Antibody, anti-human, Vio® R667, REAfinity™. Clone REA1039 recognizes the human interleukin 21 (IL-21), which is secreted by a certain subset of CD4+ T cells, called T follicular helper (Tfh) cells, also characterized by the expression of CXCR5 and ICOS and the lineage-specific transcription factor BCL6. But IL-21 production can also be found in other T helper cell lineages and natural killer T (NKT) cells. IL-21 acts in a autocrine manner on Tfh cells and is critical for antibody production by B cells, it enhances natural killer (NK) cell functions, and promotes proliferation of CD8+ T cell. | Additional information: Clone REA1039 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesCVID11, Za11
Gene, Accession #Gene ID: 59067
Catalog #130-117-423
Price$385
Order / More InfoIL-21, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific Referencesn/a
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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