CD96 (TACTILE), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD96 (TACTILE), Human |
| Clone | REA195 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD96 (TACTILE) Antibody, anti-human, PE, REAfinity™. Clone REA195 recognizes CD96, which is also known as T cell-activated increased late expression (TACTILE). CD96 is a single-pass transmembrane glycoprotein belonging to the Ig superfamily and consists of three extracellular Ig-like domains and a membrane proximal region rich in proline/serine/threonine. Expression of CD96 is found on T cells, NK cells, and on majority of CD34+CD38- acute myeloid leukemic (AML) cells. CD96 interacts with CD155, which is also known as polio virus receptor and promotes NK cell adhesion to target cells expressing CD155. CD96 is further described as a tumor marker for T cell-acute lymphoblastic leukemia (T-ALL) and AML. | Additional information: Clone REA195 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | TACTILE |
| Gene, Accession # | Gene ID: 10225 |
| Catalog # | 130-123-750 |
| Price | $335 |
| Order / More Info | CD96 (TACTILE), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Fuchs, A. et al. (2004) Cutting Edge: CD96 (Tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). J Immunol 172: 3994-3998. | Meyer, D. et al. (2009) CD96 interaction with CD155 via its first Ig-like domain is modulated by alternative splicing or mutations in distal Ig-like domains. J. Biol. Chem. 284: 2235-2244. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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