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Antigenic Specificity | IL-8, Human |
Clone | REA731 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Intracellular flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-8 Antibody, anti-human, APC, REAfinity™. Clone REA731 recognizes the human IL-8 chemokine, a heterodimer also known as interleukin 8 or CXCL8 (chemokine (C-X-C motif) ligand 8. IL-8 is secreted by macrophages, epithelial cells, airway smooth muscle cells, and endothelial cells. IL-8 plays a role in neutrophil activation, is a potent promoter of angiogenesis, and attracts neutrophils, basophils, and T cells. Clone REA731 recognizes both the 72 and 77 amino acid isoforms of human IL-8. | Additional information: Clone REA731 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | Interleukin-8, Emoctakin, GCP-1, MDNCF, MONAP, NAP-1, Protein 3-10C, CXCL8 |
Gene, Accession # | Gene ID: 3576 |
Catalog # | 130-112-016 |
Price | $142 |
Order / More Info | IL-8, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Mukaida, N. et al. (1989) Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8. J Immunol 143 (4): 1366-1371. | Matsushima, K. et al. (1989) Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL 1 and TNF. Cytokine 1 (1): 2-13. | Hebert, C. A. et al. (1990) Endothelial and leukocyte forms of IL-8. Conversion by thrombin and interactions with neutrophils. J Immunol 145 (9): 3033-3040. |