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Antigenic Specificity | TM4SF1, Human |
Clone | REA851 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | Vio Bright V423 conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TM4SF1 Antibody, anti-human, Vio® Bright V423, REAfinity™. Clone REA851 recognizes the human TM4SF1 antigen, also known as transmembrane 4 L6 family member 1. TM4SF1 is a member of the tetraspanin family, which members are involved in signal transduction events, important for the regulation of cell development, activation, growth, and motility. It is reported, that TM4SF1 suppresses the expression of CD63 and CD82, two molecules that inhibit cell mobility. TM4SF1 is highly expressed in lung, breast, colon, and ovarian carcinomas. It is also found on some endothelial cells. | Additional information: Clone REA851 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | Transmembrane 4 L6 family member 1 |
Gene, Accession # | Gene ID: 4071 |
Catalog # | 130-131-190 |
Price | $208 |
Order / More Info | TM4SF1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Marken, J. S. et al. (1992) Cloning and expression of the tumor-associated antigen L6. Proc. Natl. Acad. Sci. U.S.A. 89 (8): 3503-3507. | Marken, J. S. et al. (1994) Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody. J. Biol. Chem. 269 (10): 7397-7401. |