TCR Vβ5.3, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TCR Vβ5.3, Human |
| Clone | REA670 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TCR Vβ5.3 Antibody, anti-human, PE, REAfinity™. Clone REA670 recognizes the human variable beta 5.3 subunit of the α/β T cell receptor (TCR Vβ5.3), a member of the Ig superfamily. The TCR is a heterodimeric glycoprotein associated with the CD3 antigen. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ5.3 is a variant of the TCR β chain. α/β T cells express a diverse α/β TCR repertoire that specifically co-recognizes self or foreign antigen bound to antigen-presenting molecules, which thereby leads to T cell-mediated immunity. TCR Vβ5.3 is expressed on a subset of peripheral blood T cells. | Additional information: Clone REA670 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | TCR Vbeta5.3, TCR Vb5.3 |
| Gene, Accession # | Gene ID: 28612, 6957 |
| Catalog # | 130-110-139 |
| Price | $310 |
| Order / More Info | TCR Vβ5.3, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Born, W. et al. (1985) Rearrangement of T-cell receptor beta-chain genes during T-cell development. Proc. Natl. Acad. Sci. U.S.A. 82 (9): 2925-2929. | Bleux, C. et al. (1995) A mouse monoclonal antibody specific for the V beta 5.3 chain of the human TcR recognizes a subgroup of the mouse TcR V beta 8.2 chains. J. Leukoc. Biol. 57 (3): 491-491. | Adari, H. et al. (1995) Expression of the human T-cell receptor V beta 5.3 in Escherichia coli by thermal induction of the trc promoter: nucleotide sequence of the lacIts gene. DNA Cell Biol. 14 (11): 945-950. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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