IFN-γ, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | IFN-γ, Mouse |
| Clone | REA638 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IFN-γ Antibody, anti-mouse, PE, REAfinity™. Clone REA638 recognizes the mouse interferon-γ (IFN-γ) antigen, a secreted protein which is produced by activated T, B, and NK cells. IFN-γ is a pleiotropic cytokine responsible for macrophage activation and differentiation. It induces transcription of several proinflammatory genes, such as inducible NO synthase, cyclooxygenase-2, and IL-1β, as well as MHC proteins. IFN-γ, in synergy with other cytokines such as TNF-α, inhibits proliferation of normal and transformed cells. Immunomodulatory effects of IFN-γ are exerted on a wide range of cell types expressing the high affinity receptors for IFN-γ. | Additional information: Clone REA638 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Gamma-interferon, IFN-gamma, IFNg |
| Gene, Accession # | Gene ID: 15978 |
| Catalog # | 130-117-352 |
| Price | $240 |
| Order / More Info | IFN-γ, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Vila-del Sol, V. et al. (2008) IFN-gamma-induced TNF-alpha expression is regulated by interferon regulatory factors 1 and 8 in mouse macrophages. J Immunol 181 (7): 4461-4470. | Gray, P. W. et al. (1983) Cloning and expression of murine immune interferon cDNA. Proc. Natl. Acad. Sci. U.S.A. 80 (19): 5842-5846. | Chan, E. D. et al. (2001) IFN-gamma + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38(mapk) in a mouse macrophage cell line. Am. J. Physiol., Cell Physiol. 280 (3): 441-450. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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