CLEC2A, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CLEC2A, Human |
| Clone | REA544 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CLEC2A Antibody, anti-human, APC, REAfinity™. Clone REA544 recognizes the human CLEC2A antigen, which is a member of the C-type lectin-like domain-containing family. It enhances TCR-stimulated T cell expansion by upregulating anti-apoptotic proteins and may modulate the capacity of T cells to home to lymph nodes through SELL. It facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity. In contrast to the other CLEC2 family members AICL, CD69, and LLT1, CLEC2A is predominantly expressed in skin. | Additional information: Clone REA544 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | INPE5792, KACL, PILAR, UNQ5792, CLEC-2A |
| Gene, Accession # | Gene ID: 387836 |
| Catalog # | 130-108-680 |
| Price | $325 |
| Order / More Info | CLEC2A, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Huarte, E. et al. (2008) PILAR is a novel modulator of human T-cell expansion. Blood 112 (4): 1259-1268. | Spreu, J. et al. (2010) Interaction of C-type lectin-like receptors NKp65 and KACL facilitates dedicated immune recognition of human keratinocytes. Proc. Natl. Acad. Sci. U.S.A. 107 (11): 5100-5105. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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