CD4, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD4, Mouse |
| Clone | REA604 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD4 Antibody, anti-mouse, PE, REAfinity™. Clone REA604 recognizes the mouse CD4 antigen, a cell surface glycoprotein, which is a member of the immunoglobulin superfamily. It is also known as L3T4 or Leu-3. In mice, CD4 is expressed on T helper cells, regulatory T cells, and at lower levels on subpopulations of NKT cells and dendritic cells. It is furthermore detected on most thymocytes (CD4+CD8+ and CD4+CD8- thymocytes). CD4 interacts with MHC class II molecules on the surface of antigen-presenting cells. It increases the avidity of the interaction between T cells and antigen-presenting or target cells. | Additional information: Clone REA604 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | L3T4, T4, Leu-3, Ly-4 |
| Gene, Accession # | Gene ID: 12504 |
| Catalog # | 130-116-509 |
| Price | $71 |
| Order / More Info | CD4, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Tourvieille, B. et al. (1986) Isolation and sequence of L3T4 complementary DNA clones: expression in T cells and brain. Science 234 (4776): 610-614. | Bierer, B. E. et al. (1989) The biologic roles of CD2, CD4, and CD8 in T-cell activation. Annu. Rev. Immunol. 7: 579-599. | Parnes, J. R. et al. (1987) L3T4 and the immunoglobulin gene superfamily: new relationships between the immune system and the nervous system. Immunol. Rev. 100: 109-127. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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