PAX-6, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | PAX-6, Human |
| Clone | REA507 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PAX-6 Antibody, anti-human, PE, REAfinity™. Clone REA507 recognizes the human paired box protein PAX-6 antigen, a member of the paired box (PAX) gene family whose protein products are transcription factors involved in development. During organogenesis, PAX-6 is required for establishment of various progenitor subtypes within the central nervous system, eye, and pancreas. PAX-6 expression is maintained in a variety of cell types within each organ. PAX-6 is abundantly expressed during patterning of the optic vesicles and during specification and differentiation of the retinal pigmented epithelium. Defects in PAX-6 are responsible for various eye malformations including aniridia and Peters' anomaly. | Additional information: Clone REA507 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | AN, Oculorhombin, D11S812E, FVH1, MGDA, WAGR, AN2 |
| Gene, Accession # | Gene ID: 5080 |
| Catalog # | 130-123-250 |
| Price | $310 |
| Order / More Info | PAX-6, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Ouyang, H. et al. (2014) WNT7A and PAX6 define corneal epithelium homeostasis and pathogenesis. Nature 511 (7509): 358-361. | Ton, C. C. et al. (1991) Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region. Cell 67 (6): 1059-1074. | Klimova, L. et al. (2014) Stage-dependent requirement of neuroretinal Pax6 for lens and retina development. Development 141 (6): 1292-1302. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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