ACPP, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityACPP, Human
CloneREAL717
Host SpeciesRecombinant Human
Reactive Specieshuman
Isotypen/a
Formatphycoerythrin (PE) conjugate
Size200 µL
Concentrationn/a
ApplicationsMICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence
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DescriptionACPP Antibody, anti-human, PE, REAdye_lease™. Clone REAL717 is an antibody fragment derived from the full ACPP antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL717 recognizes the human ACPP (acid phosphatase, prostate), also known as PAP (prostatic acid phosphatase. ACPP is a non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions. ACPP has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2 of ACPP acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling. It also generates adenosine from AMP which acts as a pain suppressor. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
Immunogenn/a
Other NamesPAP (Prostatic Acid Phosphatase), 5'-NT, Ecto-5'-nucleotidase, TMPase, PAPf39
Gene, Accession #n/a
Catalog #130-126-576
Price$480
Order / More InfoACPP, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesGraddis, T. J. et al. (2011) Prostatic acid phosphatase expression in human tissues. Int J Clin Exp Pathol 4 (3): 295-306. | Veeramani, S. et al. (2005) Cellular prostatic acid phosphatase: a protein tyrosine phosphatase involved in androgen-independent proliferation of prostate cancer. Endocr Relat Cancer 12 (4): 805-822.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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