CD85g (ILT7), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD85g (ILT7), Human |
| Clone | REA100 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD85g (ILT7) Antibody, anti-human, PE, REAfinity™. The clone REA100 recognizes human CD85g, also known as immunoglobulin-like transcript 7 (ILT7), a cell surface receptor which is specifically expressed on human plasmacytoid dendritic cells (PDCs). ILT7 associates with FcεR1γ chain through positively charged arginine residue located in the transmembrane domain to form a receptor complex. Cross-linking of ILT7 results in FcεR1γ-dependent activation of an ITAM-mediated signaling pathway, which negatively influences TLR7/9 induced type I IFN production. Cross-linking of ILT7 by REA100 monoclonal antibodies inhibits type I IFN production in human PDCs. | Additional information: Clone REA100 display negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | LILRA4, ILT7 |
| Gene, Accession # | Gene ID: 23547 |
| Catalog # | 130-099-004 |
| Price | $310 |
| Order / More Info | CD85g (ILT7), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Cao, W. et al. (2006) Plasmacytoiddendritic cell-specific receptor ILT7-FcεRIγ inhibits Toll-like receptor-induced interferon production. J. Exp. Med. 203: 1399-1405. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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