IFN-γ, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityIFN-γ, Human
Clone45-15
Host SpeciesMouse
Reactive Specieshuman, nonhuman primate
IsotypeIgG1
Formatpurified
Size500 µg in 0.5 mL
Concentrationn/a
ApplicationsFlow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
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DescriptionIFN-γ Antibody, anti-human, pure-functional grade. Interferon gamma (IFN-γ) is produced by cells that are involved in inflammatory immune responses. IFN-γ is predominantly released by memory and effector CD4+ and CD8+ T cells as well as by NK cells upon activation. Quantitative analysis of IFN-γ-producing cells can provide important information on the course of immune responses. Anti-IFN?γ antibodies are designed for intracellular staining of IFN?γ-producing cells. Cells can be stimulated for IFN-γ-production, e.g. by polyclonal stimulation with mitogens. For induction of IFN?γ-production by antigen-specific T cells, cells are restimulated with respective antigen. IFN?γ can be accumulated in the cells by addition of secretion inhibitors like brefeldin A. After fixation and permeabilization of the cell sample, IFN?γ-producing cells can be stained intracellularly with Anti-IFN?γ antibodies. Staining of surface markers allows simultaneous flow cytometric analysis of subsets and activation status of the IFN-γ-producing cells.
Immunogenn/a
Other NamesIFNg, IFG, IFI
Gene, Accession #Gene ID: 3458
Catalog #130-095-743
Price$410
Order / More InfoIFN-γ, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesChaput, N. et al. (2013) Phase I clinical trial combining imatinib mesylate and IL-2: HLA-DR+ NK cell levels correlate with disease outcome. Oncoimmunology 2 (2): e23080.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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