Bcl-10, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Bcl-10, Human |
| Clone | REA1140 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | 1:50 |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Bcl-10 Antibody, anti-human, PE, REAfinity™. Clone REA1140 recognizes the signaling protein Bcl-10, which is a MALT1 substrate and ubiquitously expressed. Bcl-10, also known as CIPER, CLAP or cCARMEN, plays a role in adaptive immune response. It is able to induce NFκB activation in a NIK-dependent pathway, promotes apoptosis and initiates pro-caspase-9 maturation. | Additional information: Clone REA1140 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CIPER, CLAP, BCL10, mE10, c-E10, cCARMEN |
| Gene, Accession # | Gene ID: 8915 |
| Catalog # | 130-119-546 |
| Price | $315 |
| Order / More Info | Bcl-10, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Rebeaud, F. et al. (2008) The proteolytic activity of the paracaspase MALT1 is key in T cell activation. Nat Immunol 9 (3): 272-281. | Torres, J. M. et al. (2014) Inherited BCL10 deficiency impairs hematopoietic and nonhematopoietic immunity. J. Clin. Invest. 124 (12): 5239-5248. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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