VEGFR-1 (Flt-1), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | VEGFR-1 (Flt-1), Human |
| Clone | REA569 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | VEGFR-1 (Flt-1) Antibody, anti-human, PE, REAfinity™. Clone REA569 recognizes the human VEGFR-1 antigen, also known as Flt-1, belonging to the class III subfamily of receptor tyrosine kinases. Vascular endothelial growth factors (VEGFs) stimulate cellular responses by binding to tyrosine kinase receptors on the cell surface, causing them to dimerize, and become activated through transphosphorylation. VEGFs are produced by endothelial, hematopoietic, and stromal cells in response to hypoxia and upon stimulation by growth factors such as transforming growth factor beta (TGF-β), interleukins, or platelet-derived growth factors (PDGFs). | Additional information: Clone REA569 displays negligible binding to Fc receptors | | | | |
| Immunogen | n/a |
| Other Names | FLT1, FLT |
| Gene, Accession # | Gene ID: 2321 |
| Catalog # | 130-124-438 |
| Price | $310 |
| Order / More Info | VEGFR-1 (Flt-1), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Grunewald, F. S. et al. (2010) Structure-function analysis of VEGF receptor activation and the role of coreceptors in angiogenic signaling. Biochim. Biophys. Acta 1804 (3): 567-580. | Riccioni, R. et al. (2007) Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts. Stem Cells 25 (8): 1862-1871. | Stuttfeld, E. et al. (2009) Structure and function of VEGF receptors. Int J Biochem Mol Biol 61 (9): 915-922. | Shibuya, M. (2001) Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Struct. Funct. 26 (1): 25-35. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG