CD49e, Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD49e, Mouse/Rat
CloneHMα5-1
Host SpeciesHamster
Reactive Speciesmouse, rat
IsotypeIgG
FormatVio Bright FITC conjugate
Size9 µg in 300 µL
Concentration1:10
ApplicationsFlow cytometry
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DescriptionCD49e Antibody, anti-mouse/rat, Vio® Bright FITC. Clone HMα5-1 recognizes the mouse and rat CD49e antigen, also known as integrin alpha-5, which is a protein belonging to the integrin alpha chain family. Integrins are cell-surface receptors, expressed as heterodimers essential in various processes mediating intercellular or cellmatrix interaction. Integrin alpha-5 is composed of a heavy and a light chain linked by a disulfide bond. CD49e associates non-covalently with the integrin beta-1 (CD29) forming the very late activation antigen-5 (VLA5) complex. It is expressed on different cell types including thymocytes, mast cells, activated T cells, and splenic B cells. | | | |
Immunogenn/a
Other NamesVLA-5, Integrin alpha-5, ITGA5
Gene, Accession #Gene ID: 16402
Catalog #130-110-109
Price$90
Order / More InfoCD49e, Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesHolers, V. M. et al. (1989) Molecular cloning of a murine fibronectin receptor and its expression during inflammation. Expression of VLA-5 is increased in activated peritoneal macrophages in a manner discordant from major histocompatibility complex class II. J. Exp. Med. 169 (5): 1589-1605. | Noto, K. et al. (1995) Identification and functional characterization of mouse CD29 with a mAb. Int. Immunol. 7: 835-842. | Hemler, M. E. et al. (1990) LA proteins in the integrin family: structures, functions, and their role on leukocytes. Annu. Rev. Immunol. 8: 365-400.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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