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Antigenic Specificity | Prominin-1, Mouse |
Clone | MB9-3G8 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 30 µg in 1 mL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Prominin-1 Antibody, anti-mouse, Biotin. Clone MB9-3G8 specifically recognizes the mouse prominin-1 antigen, a glycoprotein with close structural similarity to its human ortholog, CD133. Prominin-1 is expressed on neural stem cells, for example, in the white matter of the cerebellum, on neuroepithelial tissue cells, and on various other epithelial cells in the mouse embryo. 5-10% of the neural cells found in the subventricular zone of postnatal mice have been shown to be prominin-1-positive. In the adult mouse, prominin-1 has been detected in the brain ependymal layer and in kidney tubules. |
Immunogen | n/a |
Other Names | PROM1, AC133, CD133 |
Gene, Accession # | Gene ID: 19126 |
Catalog # | 130-101-851 |
Price | $64 |
Order / More Info | Prominin-1, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Weigmann, A. et al. (1997) Prominin, a novel microvilli-specific polytopic membrane proteine of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells. Proc. Natl. Acad. Sci. U.S.A. 94: 12425-12430. | Singh, S. K. et al. (2003) Identification of a cancer stem cell in human brain tumors. Cancer Res. 63: 5821-5828. | Lee, A. et al. (2005) Isolation of neural stem cells from the postnatal cerebellum. Nat. Neurosci. 8: 723-729. | Corbeil, D. et al. (2001) Prominin: a story of cholesterol, plasma membrane protrusions and human pathology. Traffic 2: 82-91. |