CD202b (TIE-2), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD202b (TIE-2), Mouse |
| Clone | REA735 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 2x 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD202b (TIE-2) Antibody, anti-mouse, PE, REAfinity™. Clone REA735 recognizes the CD202b antigen, also known as TIE-2 or TEK. CD202b is a tyrosine-protein kinase which is mainly expressed in endothelial cells and their progenitors. CD202b is a cell-surface receptor for angiopoietins and is involved in angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, and re-organization of the actin cytoskeleton. | Additional information: Clone REA735 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | HYK, STK1, TIE-2, TIE2, TEK |
| Gene, Accession # | Gene ID: 21687 |
| Catalog # | 130-111-865 |
| Price | $465 |
| Order / More Info | CD202b (TIE-2), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Dumont, D. J. et al. (1993) The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors. Oncogene 8 (5): 1293-1301. | Jones, N. et al. (1999) Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration. J. Biol. Chem. 274 (43): 30896-30905. | Fiedler, U. et al. (2003) Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats. J. Biol. Chem. 278 (3): 1721-1727. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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