CD140b, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD140b, Mouse |
| Clone | REA634 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | APC-Vio 770 conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD140b Antibody, anti-mouse, APC-Vio® 770, REAfinity™. Clone REA634 recognizes the mouse CD140b antigen, also known as platelet-derived growth factor receptor-β (PDGFR-β), a tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB. CD140b plays a role in the regulation of embryonic development, cell proliferation, differentiation, chemotaxis, survival, and migration. CD140b is expressed on embryonic tissues and mesenchymal-derived cells in adult mice. | Additional information: Clone REA634 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | PDGF-R-beta, PDGFR-beta, PDGFR-1 |
| Gene, Accession # | Gene ID: 18596 |
| Catalog # | 130-118-469 |
| Price | $160 |
| Order / More Info | CD140b, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Seifert, R. A. et al. (1993) PDGF-AB requires PDGF receptor alpha-subunits for high-affinity, but not for low-affinity, binding and signal transduction. J. Biol. Chem. 268 (6): 4473-4480. | Tallquist, M. D. et al. (2003) Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. PLoS Biol. 1 (2): E52. | Taneda, S. et al. (2003) Obstructive uropathy in mice and humans: potential role for PDGF-D in the progression of tubulointerstitial injury. J. Am. Soc. Nephrol. 14 (10): 2544-2555. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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