CD100, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD100, Mouse |
| Clone | REA322 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | PE-Vio 770 conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD100 Antibody, anti-mouse, PE-Vio® 770, REAfinity™. Clone REA322 recognizes the mouse CD100 antigen, a single-pass type I membrane protein which is also known as semaphorin 4D (Sema4D). CD100 is strongly expressed in lymphoid tissues, especially in the thymus, as well as in the nervous tissues. It is also overexpressed by some malignancies and plays a role in tumor-induced angiogenesis similar to vascular endothelial growth factor. CD100 is a member of a family of transmembrane and secreted proteins that have been shown to act through its receptor plexin-B1 to regulate axon growth cone guidance, lymphocyte activation, and bone density. It has been shown to interact with the B cell coreceptor CD72 for enhancing B cell receptor signaling. | | Additional information: Clone REA322 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | SEMA4D, Semacl2, SEMAJ, Semcl2, coll-4 |
| Gene, Accession # | Gene ID: 20354 |
| Catalog # | 130-104-765 |
| Price | $57 |
| Order / More Info | CD100, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Furuyama, T. et al. (1996) Identification of a novel transmembrane semaphorin expressed on lymphocytes. J. Biol. Chem. 271 (52): 33376-33381. | Lu, L. et al. (2014) Changes of temporomandibular joint and semaphorin 4D/plexin-B1 expression in a mouse model of incisor malocclusion. J Oral Facial Pain Headache 28 (1): 68-79. | Zhou, H. et al. (2014) The Semaphorin 4D-Plexin-B1-RhoA signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B and ANGPTL4. Angiogenesis 17 (1): 261-274. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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