CD321 (JAM1), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD321 (JAM1), Mouse |
| Clone | REA854 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD321 (JAM1) Antibody, anti-mouse, FITC, REAfinity™. Clone REA854 recognizes the mouse CD321 antigen, a type I transmembrane glycoprotein containing two extracellular immunoglobulin-like domains. CD321 is a receptor molecule also known as junctional adhesion molecule 1 (JAM1) and is expressed on some epithelial cells, macrophages, and dendritic cells. It is involved in regulating monocyte transmigration as well as in the organization and function of antigen-presenting cells. Furthermore, CD321 acts as a ligand for the integrin LFA1, which plays a role in leukocyte transmigration. | Additional information: Clone REA854 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | JAM-A, JAM-1, F11 |
| Gene, Accession # | Gene ID: 16456 |
| Catalog # | 130-112-541 |
| Price | $56 |
| Order / More Info | CD321 (JAM1), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Malergue, F. et al. (1998) A novel immunoglobulin superfamily junctional molecule expressed by antigen presenting cells, endothelial cells and platelets. Mol. Immunol. 35 (17): 1111-1119. | Martin-Padura, I. et al. (1998) Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J. Cell Biol. 142 (1): 117-127. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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