CD252 (OX40L), Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD252 (OX40L), Rat |
| Clone | ATM-2 |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | IgG1κ |
| Format | phycoerythrin (PE) conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD252 (OX40L) Antibody, anti-rat, PE. Clone ATM-2 recognizes the rat CD252 antigen, a member of the TNF ligand superfamily, also known as OX40 ligand (OX40L) or tumor necrosis factor ligand superfamily member 4 (TNSFSF4). CD252 is constitutively expressed by splenic dendritic cells and can be upregulated on splenic B cells via stimulation with LPS. Expression of the cognate receptor CD134 (OX40) is found predominantly on activated T cells. CD252/CD134 interaction promotes the proliferation and survival of effector T cells, modulates cytokine production, suppresses the activity of natural regulatory T cells, and inhibits the generation of inducible regulatory T cells. |
| Immunogen | n/a |
| Other Names | TNFSF4, OX40L |
| Gene, Accession # | Gene ID: 89814 |
| Catalog # | 130-104-349 |
| Price | $42 |
| Order / More Info | CD252 (OX40L), Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Satake, Y. et al. (2000) Characterization of rat OX40 ligand by monoclonal antibody. Biochem. Biophys. Res. Commun. 270 (3): 1041-1048. | Paterson, D. J. et al. (1987) Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. Mol. Immunol. 24 (12): 1281-1290. | Ishii, N. et al. (2010) OX40-OX40 ligand interaction in T-cell-mediated immunity and immunopathology. Adv. Immunol. 105: 63-98. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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