Neurofilament M (160 kD), Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Neurofilament M (160 kD), Human/Mouse |
| Clone | REAL962 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | allophycocyanin (APC) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Neurofilament M (160 kD) Antibody, anti-human/mouse, APC, REAdye_lease™. Clone REAL962 is an antibody fragment derived from the full Neurofilament M (160 kD) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL962 recognizes the human and mouse Neurofilament M (160 kD) protein, also known as Neurofilament 3 and belongs to the intermediate filament (IF) family. Neurofilaments IFs are components of most eukaryotic cells, differ significantly from other cellular cytoskeletal elements and are found predominantly in cells or tissues of neuronal origin. Mutations of the Neurofilament 160 KDa gene leads to neuroaxonal damages and further to various neurological disorders. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
| Immunogen | n/a |
| Other Names | NFM, NF-M, 160 kDa neurofilament protein, NEF3, Neurofilament 3, Neurofilament medium polypeptide, Neurofilament triplet M protein |
| Gene, Accession # | n/a |
| Catalog # | 130-127-949 |
| Price | $470 |
| Order / More Info | Neurofilament M (160 kD), Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Greenwood, J. A. et al. (1993) Phosphorylation modulates calpain-mediated proteolysis and calmodulin binding of the 200-kDa and 160-kDa neurofilament proteins. J Neurochem 61 (1): 191-199. | Khalil, M. et al. (2018) Neurofilaments as biomarkers in neurological disorders. Nat Rev Neurol. 14 (10): 577-589. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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